Nindev 150mg Capsule

Details

Nindev 150mg Capsule contains Nintedanib 150mg, a prescription medicine used in adults for certain chronic lung conditions associated with progressive scarring. It is commonly prescribed for idiopathic pulmonary fibrosis and may also be used for other selected progressive fibrosing interstitial lung diseases and systemic sclerosis-associated interstitial lung disease when considered appropriate by a specialist.

Nintedanib belongs to a group of medicines known as kinase inhibitors. It works by blocking specific signalling pathways involved in the development and progression of fibrosis. By inhibiting these pathways, Nintedanib can help slow the rate at which lung function declines in appropriate patients.

Nindev should be taken exactly as prescribed by the treating doctor. The medicine requires appropriate medical supervision because treatment may involve regular monitoring of liver function and other health parameters.

What Is Nindev 150mg Capsule?

Nindev 150mg Capsule is an oral prescription medicine containing Nintedanib 150mg. Nintedanib is an antifibrotic medicine that targets signalling pathways involved in the formation and progression of fibrotic tissue.

It is used mainly in adults with certain chronic lung conditions where excessive scarring can progressively affect lung function. The medicine does not reverse existing lung scarring, but treatment can help slow the decline in lung function in appropriate patients.

Nindev may also be used in selected cases of non-small cell lung cancer in combination with docetaxel, depending on the specific cancer diagnosis and treatment plan determined by an oncology specialist.

For additional information about Nintedanib, visit MedlinePlus Nintedanib Drug Information.

Nindev 150mg Capsule Uses

Nindev is prescribed for specific conditions where Nintedanib's antifibrotic activity is clinically appropriate. Treatment should be initiated and monitored by a qualified healthcare professional experienced in managing these conditions.

Idiopathic Pulmonary Fibrosis

Nintedanib is used in adults with idiopathic pulmonary fibrosis, a chronic lung condition in which scar tissue progressively develops within the lungs. Nintedanib can help slow the rate of decline in pulmonary function.

Progressive Fibrosing Interstitial Lung Disease

Nintedanib may be prescribed for adults with chronic fibrosing interstitial lung diseases that have a progressive phenotype. These conditions can cause increasing lung stiffness and reduced respiratory function over time.

Systemic Sclerosis-Associated Interstitial Lung Disease

Nintedanib is also indicated in adults with systemic sclerosis-associated interstitial lung disease to help slow the decline in pulmonary function.

Selected Non-Small Cell Lung Cancer

In specific circumstances, Nintedanib may be used together with docetaxel for certain adults with locally advanced, metastatic or locally recurrent non-small cell lung cancer of adenocarcinoma histology after first-line chemotherapy. This use requires specialist oncology supervision.

Benefits of Nindev 150mg Capsule

Helps Slow Fibrotic Lung Disease Progression

Nintedanib targets signalling pathways involved in fibrosis and can help slow the progression of lung scarring in appropriate patients with certain chronic fibrosing lung diseases.

Supports Preservation of Lung Function

By slowing the rate of decline in pulmonary function, Nintedanib can help preserve remaining lung capacity for longer in patients for whom the medicine is appropriate.

Targets Fibrosis-Related Signalling

Nintedanib works by inhibiting specific tyrosine kinases involved in processes that contribute to fibrosis and abnormal tissue growth.

Used Across Selected Progressive Lung Conditions

Nintedanib has established uses in idiopathic pulmonary fibrosis, progressive fibrosing interstitial lung diseases and systemic sclerosis-associated interstitial lung disease in appropriate adult patients.

For related treatment options, explore our Nintabid 150mg Capsule.

You can also explore our Respiratory Care Products for other respiratory medicines.

Composition of Nindev 150mg Capsule

• Nintedanib 150mg

How Nindev 150mg Capsule Works

Nintedanib is a kinase inhibitor. It blocks several signalling pathways involved in the development of fibrosis and abnormal cell growth.

In fibrotic lung diseases, these signalling pathways can contribute to the activation and proliferation of cells involved in scar formation. By inhibiting these pathways, Nintedanib helps reduce the processes responsible for progressive fibrosis.

In selected cancer treatment, Nintedanib can also interfere with signalling involved in tumour blood-vessel formation and tumour progression.

How To Take Nindev 150mg Capsule

Take Nindev exactly according to your doctor's prescription. The capsule should be swallowed whole with water and should be taken with food.

Try to take the medicine at approximately the same times each day. Consistent administration helps maintain a regular amount of medicine in the body.

Do not chew, crush or open the soft gelatin capsule unless your healthcare professional specifically instructs you to do so.

The recommended adult dose for many approved indications is 150mg twice daily approximately 12 hours apart, but your doctor may adjust the dose or temporarily interrupt treatment depending on your medical condition and side effects.

Nindev 150mg Capsule Dosage

The dosage of Nindev is determined by the treating specialist. For many adult patients, the recommended dose of Nintedanib is 150mg twice daily, approximately 12 hours apart, taken with food.

Patients who experience certain adverse reactions may require temporary treatment interruption or a dose reduction. People with mild hepatic impairment may require a lower dose.

Do not change your dose yourself. Your doctor will decide whether treatment should continue at the same dose, be temporarily interrupted or be adjusted.

Important Safety Information

• Nindev should be used only with a valid prescription and medical supervision.
• Take the capsule with food as directed.
• Swallow the capsule whole with water.
• Tell your doctor about liver disease before starting treatment.
• Regular liver function tests may be required.
• Inform your doctor if you have bleeding problems or are taking blood-thinning medicines.
• Tell your doctor if you have recently had surgery or are planning surgery.
• Inform your healthcare professional about all prescription medicines, supplements and herbal products.
• Tell your doctor if you are pregnant or planning pregnancy.
• Do not stop or change treatment without medical advice.

Possible Side Effects of Nindev 150mg Capsule

Nintedanib may cause side effects in some patients. Commonly reported effects include diarrhoea, nausea, abdominal pain, vomiting, decreased appetite, weight loss and headache. Increased liver enzymes may also occur.

Diarrhoea

Diarrhoea is one of the commonly reported side effects of Nintedanib. Maintain adequate fluid intake and contact your doctor if diarrhoea becomes severe, persistent or difficult to control.

Nausea and Vomiting

Nausea or vomiting may occur during treatment. Taking the medicine with food as prescribed and following your doctor's dietary recommendations may help with tolerability.

Abdominal Discomfort

Some patients may experience stomach or abdominal discomfort. Inform your healthcare professional if symptoms are persistent or severe.

Liver Enzyme Changes

Nintedanib can cause changes in liver enzymes. Your doctor may therefore arrange liver-function testing before and during treatment.

Nindev 150mg Drug Interactions

Tell your doctor about all medicines and supplements you take before starting Nindev. Some medicines can affect how Nintedanib is processed in the body or may increase the risk of adverse effects.

Particular attention may be needed if you take medicines that affect bleeding risk, medicines that influence liver enzymes or other treatments that may interact with Nintedanib.

Do not start or stop another medicine without first discussing it with your doctor or pharmacist.

Nindev and Liver Function

Liver function is an important consideration during Nintedanib treatment. Your doctor may perform liver-function tests before starting treatment and periodically during therapy.

Tell your doctor immediately if you develop symptoms such as unusual tiredness, loss of appetite, persistent nausea, pain in the upper-right area of the abdomen, dark urine or yellowing of the skin or eyes.

Nindev During Pregnancy

Nintedanib may cause harm to an unborn baby. Women who could become pregnant should discuss pregnancy prevention with their healthcare professional before and during treatment.

If you become pregnant while taking Nindev, contact your doctor promptly for medical advice.

Nindev During Breastfeeding

Tell your doctor if you are breastfeeding before starting Nindev. Your healthcare professional will advise whether treatment is appropriate and whether breastfeeding should be continued during therapy.

Missed Dose

If you miss a dose of Nindev, follow the instructions provided by your doctor. Do not take two doses at the same time to make up for a missed dose.

If you are unsure what to do after missing a dose, contact your doctor or pharmacist for specific advice.

Important Usage Tips

• Take Nindev with food.
• Take it at approximately the same time each day.
• Swallow the capsule whole with water.
• Do not change the prescribed dose without medical advice.
• Attend scheduled liver-function tests.
• Report persistent diarrhoea or severe abdominal symptoms.
• Inform your doctor about bleeding disorders or anticoagulant medicines.
• Tell your doctor about pregnancy or plans to become pregnant.
• Keep all scheduled appointments with your treating specialist.

Why Regular Monitoring Is Important

Nintedanib treatment requires medical monitoring because it can affect liver function and may cause gastrointestinal and other adverse effects. Your doctor may use blood tests and clinical assessments to determine whether treatment should continue at the prescribed dose.

Monitoring also helps your healthcare professional identify side effects early and make appropriate treatment adjustments when required.

Frequently Asked Questions

What is Nindev 150mg Capsule?

Nindev 150mg Capsule is a prescription medicine containing Nintedanib 150mg. It is used in adults for certain progressive fibrosing lung diseases and selected specialist treatments.

What is Nindev 150mg Capsule used for?

Nindev is used for idiopathic pulmonary fibrosis and selected chronic progressive fibrosing interstitial lung diseases. Nintedanib may also have specialist oncology uses depending on the approved indication and treatment plan.

What is the composition of Nindev?

Nindev 150mg Capsule contains Nintedanib 150mg.

How should Nindev be taken?

Take Nindev exactly as prescribed, with food, and swallow the capsule whole with water. Do not change the dose without medical advice.

Is Nindev a prescription medicine?

Yes. Nindev 150mg Capsule is a prescription medicine and should be used under the supervision of an appropriate healthcare professional.

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For reliable medicine information, visit MedlinePlus – Nintedanib Drug Information.

Disclaimer

This product information is provided for general educational purposes and does not replace professional medical advice, diagnosis or treatment. Nindev 150mg Capsule is a prescription medicine and should be used only under the supervision of a qualified healthcare professional.

Dosage, treatment duration, monitoring and suitability vary between patients. Always follow your doctor's prescription and check the original product packaging and prescribing information for the latest details.

Specifications